Nitric Oxide redox biology in MBDM
Ahmad Nabiyar • March 1, 2021
Isolation and culture of murine bone marrow-derived macrophages (MBDM) for nitric oxide and redox biology

In the referenced paper researchers, Bailey, J. D., Shaw, A., McNeill, E.,et al., aim to establish an optimal protocol and a standardized cell culture method for the study of nitric oxide (NO)-redox biology and immunometabolism in vitro. A crucial element of this protocol includes the equipment that measures Nitric Oxide and Nitric Oxide metabolites, e.g. Nitrite/Nitrates in MBDM. Researchers report selecting and using ECO PHYSICS CLD 88 NO analyzer for its selectivity and sensitivity for Nitrite/Nitrates in Bone Marrow-derived macrophages (BMDM).

ECO PHYSICS recently visited the NASA Glenn Research Center in Cleveland, Ohio. Glenn is NASA’s only research center in the Midwest, officially named after John Glenn in March 1999. This site was established in 1941 and was incorporated into NASA in 1958. It is NASA’s third oldest research center. The purpose of the facility has evolved over the years, it was originally for aircraft propulsion studies and now it creates advanced technology for aviation and space exploration. Their facilities currently include wind tunnels, drop towers, vacuum chambers, and a research aircraft hangar. We were fortunate enough to see some of these and take some photos during our installation and training visit. Glenn is involved with many important projects, such as the International Space Station and the Artemis Program, which is NASA’s latest plan to return to the Moon. We hope to be involved in more of the great work and research that NASA Glenn will do in the future. Thank you to Krystal and Dawn for their time.